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Table 3.

Estimated odds ratio for the risk of diabetes prevalence according to the combination of low SPMA, high SPMA levels, and sex

Variable Estimated odds ratio (95% confidence interval) P-value

Female Male


SPMA (–) (n=556) SPMA (+) (n=370) SPMA (–) (n=596) SPMA (+) (n=177)
Prevalence of diabetes, n (%) 42 (6.5) 78 (16.0) 84 (10.1) 59 (27.9)
Unadjusted Reference 2.73* (1.62∼4.59) 1.61 (0.99∼2.59) 5.55** (3.26∼9.45) <0.001**
Model 1 Reference 1.26 (0.71∼2.26) 1.46 (0.85∼2.50) 3.29** (1.66∼6.54) 0.001*
Model 2 Reference 1.30 (0.73∼2.32) 1.26 (0.65∼2.45) 2.66* (1.22∼5.82) 0.032*

SPMA (–) is defined as low concentration, including the 1st tertile (0%∼33.3%) and 2nd tertile (33.3%∼66.6%) of SPMA/urine creatinine, while SPMA (+) is defined as high concentration, corresponding to the 3rd tertile (66.6%∼100%).

Model 1: adjusted for age, BMI, total cholesterol/HDL-cholesterol ratio, systolic blood pressure, diastolic blood pressure.

Model 2: adjusted for Model 1 covariates plus total physical activity, smoking status, drinking status, education level, household income.

*P<0.05, **P<0.001.

Abbreviations: SPMA, S-phenylmercapturic acid; BMI, body mass index; HDL, high-density lipoprotein.

Korean J Clin Lab Sci 2024;56:349-57 https://doi.org/10.15324/kjcls.2024.56.4.349
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