Effect of curcumin administration and LED irradiation on the epidermal cell proliferation in AD-like skin lesions induced by DNCB treatment in BALB/c mice. (A) PCNA- and TUNEL-positive cells in the epidermis of each group, stained by immunohistochmical staining and TUNEL methods, respectively. (B, C) Data shown are the mean±SE. ^***p＜0.001 compared with the vehicle group, ^###p＜0.001 compared with the DNCB group, and ^§p＜0.05, ^§§p＜0.01, ^§§§p＜0.001 compared with the curcumin and LED group (N=6).