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Relationship between Arterial Stiffness as Measured by the Cardio-Ankle Vascular Index with Body Mass Index in Healthy Elderly Subjects
Korean J Clin Lab Sci 2019;51:277-285  
Published on September 30, 2019
Copyright © 2019 Korean Society for Clinical Laboratory Science.

Kyung A Shin

Department of Clinical Laboratory Science, Shinsung University, Dangjin, Korea
Correspondence to: * Kyung A Shin
Department of Clinical Laboratory Science, Shinsung University, 1 Daehak-ro, Jeongmi-myeon, Dangjin 31801, Korea
E-mail: mobitz2@hanmail.net
* ORCID: https://orcid.org/0000-0001-5266-5627
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
An inverse correlation between obesity and arterial stiffness has been reported, but there are no consistent results in elderly subjects. This study examined the relationship between the arterial stiffness measured by the CAVI (cardio-ankle vascular index) and BMI (body mass index) in healthy elderly people. This study included 629 healthy elderly people aged 65 and over who underwent health examinations at a general hospital in Gyeonggi from July 2018 to June 2019. Metabolic syndrome was diagnosed using the criteria of the Adult Treatment Panel (ATP) III of the US National Cholesterol Education Program (NCEP). Among the criteria of NCEP-ATP III, the waist circumference and obesity criteria were based on the WHO criteria. All subjects underwent a biochemical blood test and an assessment of the CAVI. In both men and women, the CAVI was lower in the obese group than in the normal weight group. Gender (P=0.047), age (P<0.001), BMI (P<0.001), and waist circumference (P=0.008) were factors affecting the CAVI. Gender, high blood pressure, and hyperglycemia were independent positive predictors of the CAVI levels, while obesity was a negative predictor. Therefore, the CAVI and BMI showed an inverse correlation. In conclusion, there was an inverse correlation between the CAVI and BMI in the elderly, and obesity was a negative predictor of the CAVI.
Keywords : Arterial stiffness, Body mass index, Cardio-ankle vascular index

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