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Antimicrobial Effects of Essential Oils for Multidrug-Resistant Acinetobacter baumanii
Korean J Clin Lab Sci 2018;50:431-437  
Published on December 31, 2018
Copyright © 2018 Korean Society for Clinical Laboratory Science.

Chang-Eun Park1, Pil Seung Kwon2

1Department of Biomedical Laboratory Science, Molecular Diagnostics Research Institute, Namseoul University, Cheonan, Korea 2Department of Clinical Laboratory Science, Wonkwang Health Science University, Iksan, Korea
Correspondence to: Pil Seung Kwon
Department of Clinical Laboratory Science, Wonkwang Health Science University, 514 Iksandae-ro, Iksan 54538, Korea
Tel: 82-63-840-1212 Fax: 82-63-840-1219 E-mail:
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Acinetobacter baumannii is categorized as a red alert pathogen that is increasingly associated with a high mortality rate in infected patients because of its resistance to extensive antibiotics. This study evaluated the antibacterial activities of some essential oils (tee tree, rosemary, and lavender oils) against 18 clinical isolates of multidrug-resistant A. baumannii (MRAB). The carbapenemase screening Hodge test showed that all 20 strains of A. baumannii were resistant to imipenem. The identification of multidrug-resistant microbes was carried out using the VITEK system. The antimicrobial activity of essential oils was tested by a disk diffusion method against MRAB. In the disk diffusion method, tea tree showed the largest increase in inhibition size compared to lavender oil, and rosemary had no antibacterial effect. These results proved the antimicrobial effect of multidrug resistance A. baumannii. Tee tree oil would be a useful alternative natural product for the treatment and prevention of most common human pathogens and MRAB infections. This is expected to be used as an antimicrobial agent, such as hand disinfectant using natural essential oil in the future.
Keywords : Disk diffusion, Essential oils, Multidrug-resistant Acinetobacter baumannii, Tea tree

December 2018, 50 (4)
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