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Significance of Non HDL-cholesterol and Triglyceride to HDL-cholesterol Ratio as Predictors for Metabolic Syndrome among Korean Elderly
Korean J Clin Lab Sci 2018;50:245-252  
Published on September 30, 2018
Copyright © 2018 Korean Society for Clinical Laboratory Science.

Seung Bok Hong1, Kyung-A Shin2

1Department of Clinical Laboratory Science, Chungbuk Health & Science University, Cheongju, Korea
2Department of Clinical Laboratory Science, Shinsung University, Dangjin, Korea
Correspondence to: Kyung-A Shin
Department of Clinical Laboratory Science, Shinsung University, 1 Daehak-ro, Jeongmi-myeon, Dangjin 31801, Korea
Tel: 82-41-350-1408
Fax: 82-41-350-1355
E-mail: mobitz2@hanmail.net
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
We evaluated the possible clinical application of Non HDL-cholesterol and triglyceride to HDL-cholesterol ratio as a metabolic syndrome predictor for the elderly in Korea. 1,543 elderly persons aged 65 years or older who visited the health examination center of Gyeonggi Regional General Hospital from January 2015 to December 2017 and had a health checkup were enrolled in this study. Metabolic syndrome was diagnosed based on the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) standards. Abdominal obesity was assessed by the Asia-Pacific standards presented at the World Health Organization (WHO) West Pacific Region. Non-HDL-cholesterol was calculated as the difference between total cholesterol and HDL-cholesterol. The metabolic syndrome predictive power was higher for triglyceride to HDL-cholesterol ratio than for Non HDL-cholesterol. After correcting for related factors, triglyceride to HDL-cholesterol ratio was higher in the 4th quartile, which had a higher risk of developing metabolic syndrome, than in the 1st quartile. The optimal cutoff value for the triglyceride to HDL-cholesterol ratio that predicts the onset of metabolic syndrome was 2.8. triglyceride to HDL-cholesterol ratio can be a simple and practical indicator of the risk of metabolic syndrome.
Keywords : Metabolic syndrome, Non HDL-cholesterol, Triglyceride to HDL-cholesterol ratio

September 2018, 50 (3)
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