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Differences in the Antibiotic Resistance Pattern of Staphylococcus aureus Isolated by Clinical Specimens in a University Hospital in South Korea
Korean J Clin Lab Sci 2018;50:85-92  
Published on June 30, 2018
Copyright © 2018 Korean Society for Clinical Laboratory Science.

Seong-No Hong1, Joon Kim2, Hyun-Ho Sung1

1Department of Clinical Laboratory Science, Dongnam Health University, Suwon, Korea
2Department of Laboratory Medicine, Ajou University Hospital, Suwon, Korea
Correspondence to: Hyun-Ho Sung
Department of Clinical Laboratory Science, Dongnam Health University, 50 Cheoncheon-ro 74-gil, Jangan-gu, Suwon 16328, Korea Tel: 82-31-249-6414 Fax: 82-31-249-6410 E-mail:
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Information on the prevalence of S. aureus and the current antimicrobial resistance profile is necessary in selecting the appropriate treatment of S. aureus infections in any part of the world. This study examined the frequency and antibiotic resistance list of S. aureus isolates obtained from clinical specimens at one hospital in Korea. A total of 1,746 gram positive cocci collected were identified as S. aureus. S. aureus isolates were obtained from different samples including sputum (N=565; 32.4%), endotracheal aspirate (358; 20.5%), wounds (329; 18.8%), blood (137; 7.8%), urine (67; 3.8%), and pus (59; 3.4%). All 1,545 S. aureus (100%) strains screened from sputum (565; 36.6%), endotracheal aspirate (388; 25.1%), wounds (329; 21.3%), blood (137; 8.9%), urine (67; 4.3%), and pus (59; 3.8%) were sensitive to glycopeptide (vancomycin, teicoplanin), oxazolidinone (linezolid) and stretogramin (quinupristin/dalfopristin). The prevalence of resistant S. aureus was significantly (P<0.01) lower in urine, blood, pus, wounds, and sputum than in endotracheal aspirates. As a result, there was a significant difference in the antibiotic resistance of S. aureus according to the clinical specimens.
Keywords : Antibiotic resistance, Infection specimen, Staphylococcus aureus

June 2018, 50 (2)
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