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Relationship of the hs-CRP Levels with FBG, Fructosamine, and HbA1c in Non-diabetic Obesity Adults
Korean J Clin Lab Sci 2018;50:190-196  
Published on June 30, 2018
Copyright © 2018 Korean Society for Clinical Laboratory Science.

Hye Jong Oh, Cheol Won Choi

Department of Biomedical Laboratory Science, Hanlyo University, Gwangyang, Korea
Correspondence to: Hye Jong Oh
Department of Biomedical Laboratory Science, Hanlyo University, 94-13 Hallyeodae-gil, Gwangyang-eup, Gwangyang 57764, Korea Tel: 82-61-760-1126 Fax: 82-61-761-6709 E-mail:
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Obesity has been reported to be a cluster of risk factors in the pathological ecology, In particular, there is increasing evidence that inflammation-related factors are associated with diabetes. This study examined the relationship between the hs-CRP level and FBG, fructosamine, and HbA1c in 4,734 non-diabetic adults aged 20 years or older, who were approved by the National Health and Nutrition Survey in 2015. The results showed that the FBG, fructosamine, and HbA1c levels increased with increasing BMI; the hs-CRP levels were the highest in the obese group, and HOMA-IR, an index of insulin resistance, was also significantly higher in the obese group. The hs-CRP level was the highest in obese adults. The levels of FBG, fructosamine. and HbA1c, which are involved in blood glucose control, increased with increasing hs-CRP level. The FBG, fructosamine, and HbA1c levels increased significantly with increasing hs-CRP level after adjusting for various related variables. These results suggest that the obesity-induced increase in hs-CRP is a risk factor for diabetes mellitus in non-diabetic adults. Therefore, proper dietary habits and regular exercise should prevent diabetes by preventing obesity in non-diabetic adults.
Keywords : FBG, fructosamine, HbA1c, hs-CRP, Obesity

June 2018, 50 (2)
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