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Effects of Omega-3 on Lipid and Liver Function Tests
Korean J Clin Lab Sci 2018;50:183-189  
Published on June 30, 2018
Copyright © 2018 Korean Society for Clinical Laboratory Science.

Woo-Soon Choi

Department of Clinical Laboratory Science, Songho University, Hoengseong, Korea
Correspondence to: Woo-Soon Choi
Department of Clinical Laboratory Science, Songho University, 210 Namsan-ro, Hoengseong 25242, Korea Tel: 82-33-340-1141 Fax: 82-33-340-1127 E-mail:
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Omega-3 unsaturated fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are found in fish and fish oil. Recent studies have shown that omega-3 fatty acids are effective in cancer, cardiovascular disease, immune system, cirrhosis, and nervous system disorders. In particular, omega-3 was also reported to help improve hyperlipidemia and liver function tests. On the other hand, there are few cases in Korea. This study examined whether omega-3 is effective in improving hyperlipemia and liver function by taking 1 gm/day for 2 weeks. As a result, AST was decreased in the liver function test, and GGT related to alcoholic hepatitis and fatty liver showed significant results. Omega-3 has been shown to help improve the liver function. The triglyceride, total cholesterol, and low density cholesterol associated with cardiovascular disease decreased after omega-3 ingestion, particularly high density cholesterol. Omega-3 has also been shown to improve the hyperlipidemia. Comparisons between males and females before and after the ingestion of omega-3 showed significant results in AST (P<0.01) from the male group and in GGT (P<0.01) and high density cholesterol (P<0.01) from the female group. As a result, omega-3 intake can help control and improve liver function and hyperlipidemia.
Keywords : Gamma-glutamyl transferase, High density lipoprotein cholesterol, Omega-3

June 2018, 50 (2)
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