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Molecular Genetic Characteristics of Methicillin-Resistant Staphylococcus aureus Isolated from Patients and Environment of General Hospital Intensive Care Unit in a Chungnam Province, Korea
Korean J Clin Lab Sci 2018;50:110-117  
Published on June 30, 2018
Copyright © 2018 Korean Society for Clinical Laboratory Science.

Hye-Suk Kim1,†, Sung-Bae Park2,†, Sang-Ha Kim3, Sunghyun Kim2, Sung-Hee Hyun4, Young-Kwon Kim5

1Department of Laboratory Medicine, Hongsung Medical Center, Hongseong, Korea
2Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan, Busan, Korea
3Department of Laboratory Medicine, Konyang University Hospital, Daejeon, Korea
4Department of Biomedical Laboratory Science, School of Medicine, Eulji University, Daejeon, Korea
5Department of Biomedical Laboratory Science, College of Medical Sciences, Konyang University, Daejeon, Korea
Correspondence to: Young-Kwon Kim
Department of Biomedical Laboratory Science, College of Medical Sciences, Konyang University, 158 Gwanjeodong-ro, Seo-gu, Daejeon 35365, Korea Tel: 82-42-660-6371 Fax: 82-42-543-6370 E-mail: ykkim3245@konyang.ac.kr
Co-Corresponding author: Sung-Hee Hyun
Department of Biomedical Laboratory Science, School of Medicine, Eulji University, 77 Gyeryong-ro, 771 beon-gil, Jung-gu, Daejeon 34824, Korea Tel: 82-42-259-1751 Fax: 82-42-259-1759 E-mail: hyunsh@eulji.ac.kr
The first two authors contribute the same to this paper.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
In the present study, mec complex typing and SCCmec typing were performed to analyze the molecular genetic characteristics of 20 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from clinical specimens and 4 strains isolated from the ICU environments of secondary medical institutions in a Chungnam province, Korea, from June to July of 2017. Among a total of 20 MRSA strains isolated from clinical specimens, 8 cases (40%) were SCCmec type II, one case (5%) was SCCmec type IVa, and 11 cases (55%) were not-typeable in SCCmec type analysis. Among 4 MRSA isolates from the ICU environment, one strain did not have the mecA gene and 3 strains were typed as SCCmec types II, III, and IVa, respectively. Data from the present study showed that the origin of MRSA isolated from the clinical specimens was different from those from the ICU environment in most cases but the origin was concordant in one case. In this case, MRSA might be transmitted by healthcare workers to the ICU environment. Further study with a large number of cases and other hospital infection-related microorganisms will be needed. This continuous follow-up study might provide useful information on infection control in medical institutions.
Keywords : ICU, mec complex type, Molecular genetic characteristics, MRSA, SCCmec type

June 2018, 50 (2)
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