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Factors Affecting Basilar Artery Pulsatility Index on Transcranial Doppler
Korean J Clin Lab Sci 2018;50:477-483  
Published on December 31, 2018
Copyright © 2018 Korean Society for Clinical Laboratory Science.

Ho Tae Jeong1, Dae Sik Kim2, Kun Woo Kang3, Yun Teak Nam4, Ji Eun Oh5, Eun Kyung Cho2

1Department of Neurology, Chung-Ang University Hospital, Department of Medicine (Major in Neurology), Chung-Ang University Graduate School, Seoul, Korea 2Department of Clinical Laboratory Science, Dongnam Health University, Suwon, Korea 3Department of Neurology, Samsung Medical Center, Seoul, Korea 4Department of Neurology, National Health Insurance Ilsan Hospitall, Goyang, Korea 5Department of Biomedical Laboratory Science, Far East University, Eumseong, Korea
Correspondence to: Ho Tae Jeong
Department of Neurology, Chung-Ang University Hospital, 102 Heukseok-ro, Dongjak-gu, Seoul 06973, Korea
Tel: 82-2-6299-1494 Fax: 82-2-6299-1493 E-mail:
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Transcranial doppler is a non-invasive method that measures the blood flow velocity and the direction of cerebral blood vessels through the doppler principle. The pulsatility index is an index for measuring the transcranial doppler that reflects the distal vascular resistance and is used as an index for the presence and diffusion of cerebral small vessel diseases. The purpose of this study was to evaluate the risk factors affecting the basilar artery pulsatility index in ischemic stroke patients. From January 2014 to May 2015, 422 patients were selected by measuring the transcranial doppler pulsatility index, considering their basilar artery pulsatility index. Univariate analysis was performed using the basilar artery pulsatility index as a dependent variable. Multiple regression analysis was performed considering the factors affecting the pulsatility index as variables. Univariate analysis revealed age, presence of hypertension, presence of diabetes mellitus, presence of hyperlipidemia, and hematocrit (P<0.1) as factors. Multiple regression analysis showed statistically significant results with age (P<0.001), presence of diabetes (P=0.004), and presence of hyperlipidemia (P=0.041). The risk factors affecting the basilar artery pulsatility index of transcranial doppler were age, diabetes, and hyperlipidemia. Further research will be needed to increase the cerebral pulsatility index as a surrogate marker of the elderly, diabetes, and hyperlipidemia.
Keywords : Basilar artery pulsatility index, Cerebral small vessel diseases, Transcranial Doppler

December 2018, 50 (4)
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