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Optimal Cutoff Points of Rate Pressure Product in Each Stage of Treadmill Exercise Test According to the Degree of Metabolic Syndrome in Korean Adults
Korean J Clin Lab Sci 2018;50:136-143  
Published on June 30, 2018
Copyright © 2018 Korean Society for Clinical Laboratory Science.

Kyung-A Shin

Department of Clinical Laboratory Science, Shinsung University, Dangjin, Korea
Correspondence to: Kyung-A Shin
Department of Clinical Laboratory Science, Shinsung University, 1 Daehak-ro, Jeongmi-myeon, Dangjin 31801, Korea Tel: 82-41-350-1408 Fax: 82-41-350-1355 E-mail:
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The rate pressure product (RPP) is expressed as a product of the heart rate and systolic blood pressure as an index indirectly measuring the myocardial oxygen consumption, and it indicates the burden on the myocardium. The aim of this study was to determine the optimal level of RPP for preventing metabolic syndrome in a treadmill exercise test in Korean adults. Metabolic syndrome was the diagnosis of the third executive summary report on the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) criteria. According to the criteria, the metabolic syndrome diagnosis group (MetS, N=25), pre-metabolic syndrome group (Pre-MetS, N=106), and non-risk factor group (Non-MetS, N=65) were classified. The exercise stress test was performed based on the Bruce protocol. The RPP was calculated as (heart rate×systolic blood pressure)÷ 1,000. The results showed that the maximum systolic blood pressure was high despite the low daily dose reached in the diagnostic group of metabolic syndrome. The optimal threshold of the RPP at the time of the exercise treadmill test for a metabolic syndrome prediction was 12.56 mmHg×beats/min×10-3 in the first stage of the exercise stress test. The second stage of the exercise test was 16.94 mmHg×beats/min×10-3, and at the third stage of the exercise test was 21.11 mmHg×beats/min×10-3.
Keywords : Cutoff points, Metabolic syndrome, Rate pressure product, Treadmill

June 2018, 50 (2)
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