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Fig. 4.

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Effects of Niclosamide on cell viability, STAT3 expression and pro-inflammatory cytokines in LPS-stimulated RAW 264.7 cells. (A) The cytotoxicity assessed in RAW 264.7 cells treated with different doses of Niclosamide for 24 hours. (B) p-STAT3 expressions in RAW 264.7 cells were analyzed by western blot. (C) Levels of IL-6, TNF-α, and IL-1β in the cell culture supernatants were detected by ELISA. Data shown as mean±SD. One-way ANOVA was performed. *P<0.05, **P<0.01 versus LPS. ####P<0.0001 versus Media.
Abbreviations: STAT3, signal transducer and activator of transcription 3; LPS, lipopolysaccharide; IL, interleukin; TNF, tumor necrosis factor; Niclo, Niclosamide; ns, not significant.
Korean J Clin Lab Sci 2023;55:306-13 https://doi.org/10.15324/kjcls.2023.55.4.306
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