
Patterns of TP53 base transversion in TP53 mutant lung adenocarcinoma
Patterns of transversions | TP53 mutation | |
---|---|---|
Smoker (N=15) | Never smoker (N=21) | |
G>T | 2 (13.3) | 1 (4.8) |
T>G | 0 (0.0) | 0 (0.0) |
G>C | 0 (0.0) | 0 (0.0) |
C>G | 10 (66.7) | 18 (85.7) |
A>C | 1 (6.7) | 0 (0.0) |
C>A | 0 (0.0) | 0 (0.0) |
A>T | 0 (0.0) | 0(0.0) |
G>T + C>G | 1 (6.7) | 1 (4.8) |
G>T + C>A | 1 (6.7) | 0 (0.0) |
G>C + C>G | 0 (0.0) | 1 (4.8) |
N (%).
Abbreviations: G, Guanine; T, Thymine; C, Cytosine; A, Adenine.