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Table. 4.

Table. 4.

Comparison of mean values for baseline characteristics with respect to genotypes among PCOS cases for CYP11B2 (rs1799998) polymorphism

Characteristics PCOS cases (N=311, mean±SD)
rs1799998 rs4646903
TT (N=253) TC (N=47) CC (N=11) P-value TT (N=253) TC (N=47) CC (N=11) P-value
Age (years) 24.0±4.9 24.4±4.2 26.4±4.6 0.245 23.8±5.0 24.2±4.0 26.0±5.0 0.07
Age at menarche (years) 13.1±1.3 13.0±1.2 13.6±0.9 0.447 13.1±1.6 13.0±1.3 13.0±1.2 0.803
Age of onset of PCOS (years) 20.0±5.4 19.5±5.2 18.6±6.3 0.591 20.2±5.3 19.2±5.2 19.8±4.5 0.366
BMI (kg/m2) 23.8±4.39 23.6±4.0 28.4±6.2 0.003* 23.6±4.3 24.1±4.5 25.5±5.3 0.088
WHR 0.8±0.06 0.8±0.06 0.8±0.05 0.526 0.8±0.06 0.8±0.07 0.8±0.06 0.524
Cholesterol (mg/dL) 168.8±49.9 174.3±50.2 151.0±51.8 0.381 168.4±47.3 175.0±58.9 156.6±41.7 0.241
Triglycerides (mg/dL) 168.5±102.5 157.5±95.7 207.8±108.7 0.338 172.8±106.9 155.3±94.3 81.0±15.3 0.441
HDL (mg/dL) 44.8±14.4 44.7±13.8 44.8±11.4 1.00 46.1±14.4 42.0±14.7 43.0±9.7 0.079
LDL (mg/dL) 90.2±57.6 98.0±59.3 65.1±54.1 0.237 87.7±55.7 101.9±66.3 79.5±44.6 0.109
VLDL (mg/dL) 32.9±20.1 31.4±19.1 41.0±21.8 0.369 33.6±21.0 31.0±18.8 34.0±16.2 0.615

*P<0.05 statistically significant by one way ANOVA.

Abbreviations: See Table 1, 2; HDL, high density lipoprotein; LDL, low density lipoprotein; VLDL, very low density lipoprotein.

Korean J Clin Lab Sci 2022;54:316-24 https://doi.org/10.15324/kjcls.2022.54.4.316
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