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Table. 1.

Table. 1.

Main characteristics of the studies included in the systematic review

Study Population Region Sample
(control)
Serum marker OR (95% CI)
Chen, CH 2021 AIS Taiwan 60 (14) GFAP 1.18 (0.91∼1.52)
NFL 2.22 (1.27∼3.88)
Chen, Z 2021 AIS China 151 (40) IL-33 0.981 (0.965∼0.997)
Dong 2020 CHD/IS China 11,015 aCL lgPoly 1.15 (1.06∼1.25)
ab2GPI IgG 1.49 (1.2∼1.84)
ab2GPI lgA 1.57 (1.31∼1.88)
Garcia∼Carmona 2022 IS Spain 156 NT-proBNP 1.001 (1∼1.002)
Harpaz 2021 IS Singapore 515 NT-proBNP 8.6 (3.98∼18.6)
Cortisol 4.23 (2.04∼8.75)
IL-6 3.05 (1.51∼6.16)
S100b 4.06 (1.95∼8.44)
Ma 2021 Hypertensive/IS China 92 GFAP 1.145 (1.012∼1.295)
Lp-PLA2 1.152 (1.042∼1.274)
CTLA-4 1.276 (1.117∼1.459)
IMA 1.213 (1.041∼1.414)
Marta∼Enguita 2021 AIS Spain 413 CRP 1.02 (1.01∼1.03)
Calprotectin 4.6 (2.86∼7.4)
Mengozzi 2020 TIA/Lacunar stroke UK 80 CRP 1.14 (1.01∼1.286)
Ramos∼Pachon 2021 AIS Spain 1,170 D-dimer 1.59 (1.31∼1.92)
NT-proBNP 1.09 (0.89∼1.34)
Schwedheim 2021 AIS Germany 374 (167) Trimethyllysine 1.327 (0.941∼1.87)
Silva∼Candal 2021 IS Spain 4,775 CRP 0.94 (0.83∼1.06)
Yang, X 2021 AIS China 415 D-dimer 2.29 (1.7∼3.08)
Zhang, M 2021 AIS China 436 BNP 1.002 (1.001∼1.003)
Zhao, J 2020 AF/IS China 913 NT-proBNP 3.635 (2.216∼5.963)

Abbreviations: OR, odds ratio; AIS, acute ischemic stroke; CHD, coronary heart disease; IS, ischemic stroke; TIA, transient ischemic attack; AF, atrial fibrillation; CI, confidence interval; GFAP, glial fibrillary acidic protein; NFL, neurofilament light chain; IL, interleukin; NT-proBNP, N-terminal pro-brain natriuretic peptide; Lp-PLA2, lipoprotein-associated phospholipase A2; CTLA-4, cytotoxic T-lymphocyte-associated protein 4; IMA, ischemia-modified albumin; BNP, brain natriuretic peptide.

Korean J Clin Lab Sci 2022;54:256-64 https://doi.org/10.15324/kjcls.2022.54.4.256
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