A schematic diagram showing the effect of miR-30a-5p and Dex in LPS-induced BV2 cell. Co-treatment with miR-30a-5p and Dex inhibited LPS-induced BV2 cells inflammatory response. The results showed that decreased NF-κB translocation and pro-inflammatory cytokines. In addition, miR-30a-5p and Dex alleviated MAPK signaling pathway and NLRP3 inflammasome activation. The inflammatory mediators iNOS, COX-2 and NO also tend to decrease.
© 2022 Korean J Clin Lab Sci
