Inhibition of COX-2, iNOS and NO expression by miR-30a-5p and Dex in LPS-induced BV2 cells. BV2 cells were transfected with miRNA-30a-5p (50 nM) for 24 h, then pretreated with Dex (20 μg/mL) for 24 h, followed by treatment with LPS (1 μg/mL) for 24 h. (A, B) COX-2 and iNOS were detected by western blot. (C) The NO concentration in supernatant was using Griess reagent. Data are presented as the means±S.D. Values of *P<0.05, **P<0.01, ***P<0.001 versus control; #P<0.05 compared with LPS group.
© 2022 Korean J Clin Lab Sci
