miR-30a-5p and Dex decrease nuclear NF-κB translocation in LPS- induced BV2 cells. BV2 cells were transfected with miRNA-30a-5p (50 nM) for 24 h, then treated Dex (20 μg/mL) and LPS (1 μg/mL) for 24 h. (A, B) The translocation of NF-κB was detected by western blot. Quantification of NF-κB ratio normalized onto β-actin in cytosolic protein and Lamin-B1 in nucleus protein were represented in bar graph. Data are presented as the means±S.D. Values of *P<0.05, **P<0.01 versus control; #P<0.05 compared with LPS group.
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