The Korean Journal of Clinical Laboratory Science : eISSN 2288-1662 / pISSN 1738-3544

Table. 1.

Table. 1.

Interpretation guidelines for antibiotic susceptibility tests of Candida species

Antifungal agent Organisms MIC range (μg/mL) Source
S SDD I R
Amphotericin B
Candida species ≤1 2 ≥4 JCM
Fluconazole
C. albicans ≤2 4 ≥8 CLSI
C. glabrata ≤32 ≥64 CLSI
C. krusei - - - -
C. parapsilosis ≤2 4 ≥8 CLSI
C. tropicalis ≤2 4 ≥8 CLSI
Voriconazole
C. albicans ≤0.12 0.25∼0.5 ≥1 CLSI
C. glabrata - - - -
C. krusei ≤0.5 1 ≥2 CLSI
C. parapsilosis ≤0.12 0.25∼0.5 ≥1 CLSI
C. tropicalis ≤0.12 0.25∼0.5 ≥1 CLSI
Flucytosine
Candida species ≤4 ≥32 FDA

JCM-wild-type MIC distributions and epidemiological cut off values for Amphotericin B, flucytosine, and itraconazole. Candida species as determined by CLSI broth microdilution.

Abbreviations: I, intermediate; MIC, minimal inhibitory concentration; R, resistant; S, susceptible; SDD, susceptible dose dependent; JCM, Japan collection of microorganisms; CLSI, clinical and laboratory standards institute; FDA, U.S. Food and Drug Administration.

Korean J Clin Lab Sci 2022;54:133-41 https://doi.org/10.15324/kjcls.2022.54.2.133
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