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Table. 5.

Table. 5.

SARS-CoV-2 diagnostic tests platforms

Viral RNA test: RT-qPCR Viral RNA test: RT-LAMP, CRISPR-Cas Viral genome: NGS Viral antigen tests Serological antibody tests
Infection status H H H H L
Immunity status L L L L H
Genome sequencing Possible Impossible Impossible Impossible Impossible
Accuracy H H H M Less than H,
more than M
Rapid L Less than H,
more than M
L H H
User friendly L Less than H,
more than M
L H H
Accessibility L Less than H,
more than M
L H H
Affordability Less than M,
more than L
Less than H,
more than M
L H H
Point of care Impossible Impossible Impossible Possible Possible
Sample preparation Difficult M Difficult Easy Easy
Cross reactivity Impossible Impossible Impossible Possible Possible
Airway swab, sputum Yes Yes Yes No No
Blood, serum Yes Yes Yes Yes Yes

Abbreviations: RT-qPCR, reverse transcription quantitative polymerase chain reaction; RT-LAMP, reverse transcription loop mediated isothermal amplification; CRISPR-Cas, clustered regularly interspaced short palindromic repeat-caspase; NGS, next generation sequencing; H, high; L, low; M, moderate.

References [8, 14].

Korean J Clin Lab Sci 2022;54:79-94 https://doi.org/10.15324/kjcls.2022.54.2.79
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