The Korean Journal of Clinical Laboratory Science : eISSN 2288-1662 / pISSN 1738-3544

Table. 1.

Table. 1.

General characteristics of participants according to the hsCRP and uric acid levels (N=17,395)

Variable Low hsCRPa Moderate hsCRPa High hsCRPa P-value
Low uric acidb
(N=11,396)
High uric acidb
(N=1,172)
Low uric acidb
(N=2,893)
High uric acidb
(N=514)
Low uric acidb
(N=1,179)
High uric acidb
(N=241)
BMI (kg/m2) 23.0±0.04 24.6±0.11 25.2±0.08 27.3±0.21 25.1±0.15 28.4±0.35 <0.001c
hsCRP (mg/L) 0.45±0.01 0.53±0.01 1.64±0.01 1.71±0.03 6.21±0.13 5.65±0.22 <0.001c
Uric acid (mg/dL) 4.8±0.01 7.6±0.03 5.1±0.03 7.8±0.05 5.0±0.04 7.7±0.07 <0.001c
Obesity (BMI≥25 kg/m2) 3,050 (26.8) 528 (45.1) 1,424 (49.2) 337 (65.6) 540 (45.8) 163 (67.6) <0.001d
Severe obesity (BMI≥30 kg/m2) 262 (2.3) 84 (7.2) 267 (9.2) 108 (21.0) 139 (11.8) 74 (30.7) <0.001d
Morbid obesity (BMI≥35 kg/m2) 21 (0.2) 8 (0.7) 39 (1.3) 19 (3.7) 26 (2.2) 18 (7.5) <0.001d
Age, years 44.1±0.3 38.1±0.6 49.0±0.4 39.9±0.8 49.1±0.6 40.0±1.3 <0.001c
Sex, male (%) 4,538 (39.8) 896 (76.5) 1,311 (45.3) 388 (75.5) 541 (45.9) 163 (67.6) <0.001d
Education, N (%) <0.001d
Elementary school or lower 2,458 (21.6) 197 (16.8) 755 (26.1) 87 (16.9) 348 (29.5) 43 (17.8)
Middle school 1,433 (12.6) 170 (14.5) 355 (12.3) 54 (10.5) 134 (11.4) 39 (16.2)
High school 3,480 (30.5) 348 (29.7) 879 (30.4) 173 (33.7) 327 (27.7) 74 (30.7)
College or higher 4,025 (35.3) 457 (39.0) 904 (31.2) 200 (38.9) 370 (31.4) 85 (35.3)
Household income (10,000 KRW/month) 469.3±7.2 489.9±12.5 428.7±9.7 459.2±17.3 408.9±12.1 436.1±26.3 <0.001c
Drinking status, N (%) <0.001d
Non drinking 6,869 (60.3) 493 (42.1) 1,753 (60.6) 218 (42.4) 721 (61.2) 116 (48.1)
<1 times/month 1,605 (14.1) 173 (14.8) 386 (13.3) 67 (13.0) 138 (11.7) 30 (12.4)
≥1 times/month 1,233 (10.8) 148 (12.6) 284 (9.8) 81 (15.8) 111 (9.4) 34 (14.1)
≥1 times/week 1,223 (10.7) 240 (20.5) 314 (10.9) 99 (19.3) 153 (13.0) 43 (17.8)
Daily 466 (4.1) 118 (10.1) 156 (5.4) 49 (9.5) 56 (4.7) 18 (7.5)
Smoking status, N (%) <0.001d
Non smoker 7,654 (67.2) 539 (46.0) 1,719 (59.4) 224 (43.6) 698 (59.2) 105 (43.6)
Former smoker 2,076 (18.2) 316 (27.0) 616 (21.3) 154 (30.0) 256 (21.7) 69 (28.6)
Current smoker (sometimes) 251 (2.2) 56 (4.8) 69 (2.4) 13 (2.5) 35 (3.0) 6 (2.5)
Current smoker (everyday) 1,415 (12.4) 261 (22.3) 489 (16.9) 123 (23.9) 190 (16.1) 61 (25.3)
Stress awareness, N (%) 0.015d
Low 1,897 (16.6) 171 (14.6) 524 (18.1) 92 (17.9) 228 (19.3) 42 (17.4)
Below average 6,465 (56.7) 709 (60.5) 1,601 (55.3) 274 (53.3) 606 (51.4) 129 (53.5)
Above average 2,518 (22.1) 238 (20.3) 634 (21.9) 131 (25.5) 287 (24.3) 58 (24.1)
High 516 (4.5) 54 (4.6) 134 (4.6) 17 (3.3) 58 (4.9) 12 (5.0)
Average sleep time (hour/day) 5.30±0.01 5.40±0.03 5.21±0.02 5.32±0.04 5.24±0.04 5.37±0.07 <0.001c
Physical activity (MET minutes/week) 1,258.0±23.8 1,422.6±67.9 1,239.6±45.1 1,197.1±76.0 1,297.5±90.0 1,432.5±167.5 0.196c
Elevated fasting glucosee, N (%) <0.001d
No 7,803 (68.5) 769 (65.6) 1,588 (54.9) 265 (51.6) 648 (55.0) 124 (51.5)
Yes 3,593 (31.5) 403 (34.4) 1,305 (45.1) 249 (48.4) 531 (45.0) 117 (48.5)
Hypertensionf, N (%) <0.001d
No 7,448 (65.4) 677 (57.8) 1,470 (50.8) 234 (45.5) 600 (50.9) 105 (43.6)
Yes 3,948 (34.6) 495 (42.2) 1,423 (49.2) 280 (54.5) 579 (49.1) 136 (56.4)
Elevated triglycerideg, N (%) <0.001d
No 7,837 (68.8) 632 (53.9) 1,616 (55.9) 206 (40.1) 719 (61.0) 117 (48.5)
Yes 3,559 (31.2) 540 (46.1) 1,277 (44.1) 308 (59.9) 460 (39.0) 124 (51.5)
Reduced HDL cholesterolh, N (%) <0.001d
No 8,176 (71.7) 785 (67.0) 1,674 (57.9) 280 (54.5) 640 (54.3) 115 (47.7)
Yes 3,220 (28.3) 387 (33.0) 1,219 (42.1) 234 (45.5) 539 (45.7) 126 (52.3)
Abdominal obesityi, N (%) <0.001d
No 8,956 (78.6) 774 (66.0) 1,636 (56.6) 219 (42.6) 694 (58.9) 78 (32.4)
Yes 2,440 (21.4) 398 (34.0) 1,257 (43.4) 295 (57.4) 485 (41.1) 163 (67.6)

Values are presented as weighted mean±weighted standard error or weighted percent.

aLow hsCRP was defined when 1.00 mg/L or less, moderate hsCRP was defined when 1.00∼3.00 mg/L was present, and high hsCRP was defined when 3.00 mg/L or more was present.

bFor premenopausal women, the low uric acid is 0.9∼5.7 mg/dL and the high uric acid is 5.8∼13.6 mg/dL. For men and postmenopausal women, the low uric acid is 0.9∼7.0 mg/dL and the high uric acid is 7.1∼13.6 mg/dL.

cCalculated by complex samples general linear model.

dCalculated by complex samples chi-square test.

eElevated fasting glucose was defined as a glucose level of at least 100 mg/dL or when a subject was receiving oral hypoglycemic agents or insulin therapy.

fHypertension was given when systolic blood pressure was 130 mmHg higher or diastolic blood pressure was 85 mmHg or higher or when a study participant was receiving antihypertensive medication.

gElevated triglyceride was defined as a concentration of 150 mg/dL or greater or when a study participant was receiving treatment for dyslipidemia.

hReduced HDL cholesterol was defined as level <40 mg/dL in men and <50 mg/dL in women.

iAbdominal obesity was defined as a waist circumference greater than 90 cm in men and 85 cm in women.

Abbreviations: BMI, body mass index; HDL, high-density lipoprotein; MET, metabolic equivalent of task; hsCRP, high sensitivity c-reactive protein; OR, odds ratio.

Korean J Clin Lab Sci 2021;53:342-52 https://doi.org/10.15324/kjcls.2021.53.4.342
© 2021 Korean J Clin Lab Sci