The associated SNPs (
| Gene | Chr | No. | SNP | BP | Function | A1 | A2 | MAF | OR (95% CI) | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Case (N=193) |
Control (N=3,228) |
||||||||||
| 13 | G1 | rs17071545 | 78988115 | Intronic | A | G | 0.166 | 0.107 | 1.61 (1.21∼2.13) | 9.00×10−4 | |
| G2 | rs1475797 | 78991826 | Intronic | A | C | 0.288 | 0.201 | 1.58 (1.25∼2.00) | 1.05×10−4 | ||
| G3 | rs2783122 | 79001279 | Intronic | G | A | 0.316 | 0.218 | 1.67 (1.33∼2.10) | 9.76×10−6 | ||
| G4 | rs1408049 | 79011653 | Intronic | G | C | 0.314 | 0.218 | 1.66 (1.32∼2.09) | 1.33×10−5 | ||
| I1 | rs7990344 | 78957081 | Intronic | C | T | 0.303 | 0.216 | 1.59 (1.26∼2.00) | 9.53×10−5 | ||
| I2 | rs8002042 | 78958688 | Intronic | A | G | 0.286 | 0.209 | 1.52 (1.203∼1.93) | 4.75×10−4 | ||
| I3 | rs1577418 | 78959508 | Intronic | A | C | 0.303 | 0.216 | 1.59 (1.26∼2.00) | 9.53×10−5 | ||
| I4 | rs17071512 | 78960018 | Intronic | C | T | 0.159 | 0.103 | 1.57 (1.182∼2.11) | 2.00×10−3 | ||
| I5 | rs1335370 | 78960767 | Intronic | T | A | 0.303 | 0.216 | 1.59 (1.26∼2.00) | 9.53×10−5 | ||
| I6 | rs6563113 | 78962136 | Intronic | G | A | 0.286 | 0.209 | 1.52 (1.203∼1.93) | 4.75×10−4 | ||
| I7 | rs1335368 | 78974432 | Intronic | A | G | 0.308 | 0.219 | 1.60 (1.277∼2.02) | 5.54×10−5 | ||
| I8 | rs9565510 | 78982351 | Intronic | G | A | 0.312 | 0.219 | 1.62 (1.294∼2.04) | 3.22×10−5 | ||
| I9 | rs7339303 | 78988866 | Intronic | A | G | 0.294 | 0.212 | 1.56 (1.238∼1.97) | 1.74×10−4 | ||
| I10 | rs9574434 | 78993542 | Intronic | C | T | 0.313 | 0.220 | 1.62 (1.293∼2.04) | 3.22×10−5 | ||
| I11 | rs2760106 | 78996990 | Intronic | C | A | 0.313 | 0.218 | 1.64 (1.307∼2.06) | 2.16×10−5 | ||
| I12 | rs2783119 | 78997119 | Intronic | A | G | 0.295 | 0.211 | 1.58 (1.253∼1.99) | 1.11×10−4 | ||
| I13 | rs2783121 | 79001230 | Intronic | T | C | 0.270 | 0.189 | 1.60 (1.245∼2.06) | 2.53×10−4 | ||
| I14 | rs2760105 | 79007868 | Intronic | G | A | 0.297 | 0.210 | 1.59 (1.266∼2.01) | 7.94×10−5 | ||
| I15 | rs987284 | 79021985 | intronic | C | A | 0.314 | 0.218 | 1.65 (1.317∼2.08) | 1.58×10−5 | ||
| I16 | rs1212082 | 79024769 | 3_UTR | A | G | 0.293 | 0.209 | 1.58 (1.254∼2.00) | 1.16×10−4 | ||
Residential area, age, and sex were included as covariates in this study.
Abbreviations: Chr, chromosome; BP, base pair; A1, minor allele; A2, major allele; MAF, minor allele frequency; OR, odds ratio; CI, confidence interval; G of No., genotyped SNP’s number; I of No., imputed SNP’s number.
