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Table. 5.

Table. 5.

Patterns of FQ resistance determinants among 56 ciprofloxacin-resistant E. coli isolates according to ST

ST No. of isolates (%) Amino acid substitution PMQR gene
gyrA parC parE aac-Ib-cr qnrB qnrS
131 10 (17.9) S83L, D87N S80I, E84V - - - -
8 (14.3) S83L, D87N S80I, E84V - + - -
4 (7.1) S83L, D87N S80I, E84V - + + -
4 (7.1) S83L, D87N S80I, E84V - - + -
2 (3.6) S83L, D87N S80I L416F - - -
1 (1.8) S83L, D87N S80I - + - +
1 (1.8) S83L, D87N S80I - + - -
1 (1.8) S83L, D87N S80I - - - -
1193 7 (12.5) S83L, D87N S80I L416F - - -
3 (5.4) S83L, D87N S80I - - - -
2 (3.6) S83L, D87N S80I L416F - + -
1 (1.8) S83L, D87N S80I, E84V - - - -
405 1 (1.8) S83L, D87N S80I, E84V - + - -
1 (1.8) S83L, D87N S80I L416F - - -
1 (1.8) S83L, D87N S80I - - + -
69 1 (1.8) S83L, D87N S80I, E84V - + - -
93 1 (1.8) S83L, D87N S80I - - - -
224 1 (1.8) S83L, D87N S80I - - - -
648 1 (1.8) S83L, D87N S80I - - - -
2003 1 (1.8) S83L, D87N S80I - + - -
2179 1 (1.8) S83L S80I - + + -
2599 1 (1.8) S83L, D87N S80I - + - -
4204 1 (1.8) S83L, D87N S80I L416F - - -
5150 1 (1.8) S83L, D87N S80I - -  -  -

Abbreviations: FQ, fluoroquinolone; ST, sequence type; PMQR, plasmid-mediated quinolone resistance; S, serine; L, leucine; D, aspartic acid; N, asparagine; I, isoleucine; E, glutamic acid; V, valine; F, phenylalanine.

Korean J Clin Lab Sci 2021;53:217-24 https://doi.org/10.15324/kjcls.2021.53.3.217
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