The Korean Journal of Clinical Laboratory Science : eISSN 2288-1662 / pISSN 1738-3544

Table. 9.

Table. 9.

Basic core processes to support laboratory biosafety practices when handling specimens from a patient under investigation for COVID-19a

Topic Processes to consider
Training - Proper collection of specimens - Donning and doffing of PPEb - Packaging and shipping of category B specimensc - Strategies for waste managementd
Equipment - Centrifuge with sealed rotor or safety cupse - Certified BSCe - Use of a point-of-care device outside the BSCe
Inventory control - Adequate supply of specimen collection devices - Appropriate disinfection materialsf - Adequate transport materials (for on-site and off-site transport)
Communication - Open lines with the medical care team - Collaborations in place with the state/local public health laboratory

Abbreviations: BSC, biological safety cabinet; PPE, personal protective equipment.

aAll procedures in the laboratory are performed based on a risk assessment. Personnel handling any specimen in the laboratory use standard precautions at biosafety level 2.

bIn situations in which aerosols and droplets are produced and respiratory protection such as fit testing for an N95 respirator are not available, a physical barrier such as a splash shield while using a surgical mask may be considered.

cPersonnel are trained in the proper safety, packaging, and shipping regulations for UN3373 Biological Substances, Category B when transporting specimens from a person under investigation for coronavirus disease 2019 (COVID-19).

dFollow standard procedures used in the laboratory for disposal of specimens that might contain other respiratory pathogens such as the seasonal influenza virus.

eWhen a certified BSC is not available and there is a potential for general aerosols or droplets, or if instruments such as a centrifuge with safety cups or sealed rotors or a point-of-care device cannot be used inside a BSC, use extra precaution to provide a barrier between the specimen and personnel such as a mask or respirator plus other physical barriers such as a splash shield and other appropriate PPE.

fUse an Environmental Protection Agency–registered hospital disinfectant with label claims effective against respiratory viral pathogens while following the manufacturer’s recommendations for use.

Korean J Clin Lab Sci 2020;52:284-95
© 2020 Korean J Clin Lab Sci