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Table. 2.

Table. 2.

Relation between alloantibody development and several variables in the studied multi-transfused patients with β-thalassemia major

Variables Non-alloimmunized Alloimmunized P-value
Number of patients 192 12 -
Age/years 0.243
Mean±SD (range) 11±5 (2∼27) 12±3 (9∼16)
Sex 0.293
Male 98 (51) 8 (66.7)
Female 94 (49) 4 (33.3)
ABO blood groups 0.920
A 84 (44) 6 (50)
B 42 (22) 2 (17)
O 62 (32) 4 (33)
AB 4 (2) 0 (0)
RhD blood group 0.174
Positive 188 (98) 11 (92)
Negative 4 (2) 1 (8)
Age at first transfusion 0.042
<2 years 177 (92.2) 9 (75)
≥2 years 15 (7.8) 3 (25)
Frequency of blood transfusion/Years 0.893
<12 units/year 14 (7.3) 1 (8.3)
≥12 units/year 178 (92.7) 11 (91.7)
Total number of transfused RBC units 0.878
Mean±SD (range) 197±204 (14∼790) 206±73 (108∼384)
History of transfusion reaction 0.003
Positive 90 (47) 11 (91.7)
Negative 102 (53) 1 (8.3)
Splenectomy 0.114
Yes 42 (22) 5 (41.6)
No 150 (78) 7 (58.4)
Korean J Clin Lab Sci 2020;52:98-104 https://doi.org/10.15324/kjcls.2020.52.2.98
© 2020 Korean J Clin Lab Sci